Thesis Vs Alpha Brain Vs NooCube: Which Nootropic is Better?

I compare Thesis nootropics, Alpha Brain and NooCube to see which nootropic is best.

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In order to live a healthy, focused, productive and enjoyable life, it’s essential to support your body in any way that you possibly can. This support can look different from person to person, based on the specific issues that a person may be facing. For many Americans, fatigue, brain fog and lack of focus can be major challenges, all relating to overall brain health.

There is brain health support available that is safe and effective if you’re trying to boost things like paying attention to a task, concentration, productivity, energy and motivation. There are different nutrients, botanicals and bioactive compounds that have nootropic actions when taken on a pretty regular basis. These nootropic supplements act as a vasodilator for the small arteries and veins that are located in the brain. This increases blood circulation within the brain and increases the number of nutrients being absorbed in a way that’s very beneficial. Many nootropics are also stimulants that get the blood flowing and the brain working.

For a lot of people, finding a nootropic supplement is something that they have never had to do before. Even people who have used prescription ADHD medications don’t really understand the benefits of nootropics. I covered this in the best nootropics for people with ADHD and anxiety, and also in my thesis nootropics vs adderall to see if Adderall or a nootropic is better to take.

This article is designed to help you start your search, focusing on three top nootropic supplements: Thesis, Alpha Brain and NooCube. Before I break down the specific features of these products, I want to share with you a little bit about my experience with nootropics.

Why I Searched for Nootropics: Thesis Vs. Alpha Brain Vs. NooCube

When I was younger, I was prescribed Adderall by my pediatrician after being formally diagnosed with ADHD. I had a lot of trouble focusing on a task, especially what I was expected to accomplish at school. I always felt like I lost my train of thought. Even as an adult, I still suffer from these issues while I’m at work. My symptoms tend to get worse when I’m tired or run down.

After taking Adderall off and on for a number of years, I became frustrated with the side effects. It frequently gave me a headache, stomachache and I wasn’t easily able to stop taking it. I would experience withdrawal symptoms very soon after trying to stop my prescription. I came across a natural alternative that had the potential to help my ADHD symptoms without any addiction issues or side effects. Nootropics were potentially my saving grace, and I had excellent results after trying them out for the first time.

Overview of Thesis

thesis nootropic personalized for adhd

Thesis claims to offer high-quality nootropics that can be taken regularly to help with various aspects of your cognitive health. This is a non reputable brand that was originally known as FindMyFormula. Not only do they sell nootropics, but they have a personalized method of obtaining the blend that’s right for your needs. Thesis uses ingredients (just like every other nootropic) such as functional mushrooms, amino acids, vitamins, plant-based adaptogens and the compound acetylcholine to produce results. The end result is a supplement that can protect the brain from cognitive decline, toxins, fatigue and damage caused by stress. Thesis Nootropics claims that it can help boost your concentration, focus, memory and ability to learn and retain knowledge.

The Nootropic Formula

When you first stop by the Thesis website, you’ll be asked to complete a questionnaire. After providing some basic information about your health and lifestyle, Thesis will make a recommendation regarding what nootropic blend will be most beneficial for you. Unlike other supplement brands that require a sample in order to make a personalized recommendation, Thesis is very quick and to the point. All of your information is kept private, and you can adjust your blend as needed.

Not all of the ingredients that are offered by Thesis will be included in your supplement. However, the most common options are alpha GPC, choline, gingko biloba, theobromine, lion’s mane, agmatine, vitamin B12, NAC, ginseng, DHA, artichoke extract, TAU, ashwagandha, sage extract and caffeine.

What I Like

bathroom medicine cabinet with thesis nootropics

I love the personalized approach that so many supplement companies are now offering. Instead of trying a one-size-fits-all approach that might not provide you with all of the necessary ingredients that you need, your data can be used to tailor your product. I didn’t think the questionnaire was lengthy at all, and it was only a few minutes before I had a recommendation that I could go ahead and purchase.

What I Don’t Like

You’ll find minimal information on the Thesis website, unless you choose to fill in their questionnaire. Then, you’re taken to an area of the site where you can find out about the actual products that you can purchase, how much they’re going to cost, etc. The brand does share some information about the ingredients that they use, so you can at least do a little preliminary research before you proceed.

Final Verdict

Thesis nootropics are unique because of the personalization aspect of ordering. The cost is reasonable for these products, similar to Alpha Brain or even 10x Brain ADHD gummies.

Overview of Alpha Brain

cutting board with alpha brain supplements

Support your cognitive functions such as memory, mental speed and focus by using Alpha Brain. This is a nootropic supplement that can help you think better under pressure, assist with stress and even boost your ability to remember names and phrases. Your reaction time can even be improved with the regular use of Alpha Brain.

To date, over one million bottles of Alpha Brain have been sold. You can calm the chaos in your brain and get into a better flow state, and there are other products that are part of the Alpha lineup that can be combined with their Brain variety in order to increase the benefits that you experience. This is an excellent product because it takes into account so many different processes in the brain. It even accounts for essential nervous system function.

The Nootropic Formula

Capsules of alpha brain

The nootropic formula in Alpha Brain is a proprietary blend that includes ingredients such as cat’s claw, L-theanine, L-tyrosine, bacopa, L-leucine, alpha-GPC, oat straw extract and phosphatidylserine. These ingredients improve cellular function in the brain, neuron communication and support neurotransmitter production so you can promote alpha brain wave production at a more optimum rate.

What I Like

This is a completely caffeine-free formula, which I absolutely love. I don’t tolerate caffeine very well, and a lot of nootropics utilize caffeine in order to produce effects. Alpha Brain shouldn’t result in any kind of jitters or anxiety when you take it.

What I Don’t Like

Because the formula of Alpha Brain is based off of proprietary blends, you won’t find specific values included for each of the ingredients in the product. Rather, you simply know that you’re getting 650 milligrams of the Omnit Flow blend, 240 milligrams of the Omnit Focus blend and 60 milligrams of the Omnit Fuel blend.

Cost and Where to Buy

You can purchase Alpha Brain by visiting the Onnit website, which is located at https://www.onnit.com/alphabrain/. The original price of Alpha Brain (for a one-time purchase) is $79.95, but the price has been temporarily dropped down to $63.96 at the time of writing this article.

Overview of NooCube


If you’re looking to gain razor sharp focus, improve your problem-solving skills, boost memory and alertness while also reducing brain fog, NooCube is an excellent supplement to consider. By providing cognitive support from natural ingredients, you can avoid having to take a prescription medication that comes with addiction risks and unwanted side effects. NooCube has been used for everything from improving your athletic performance to getting through a stressful project at work.

If you have been feeling like you’re lazy, unable to focus, your brain just doesn’t seem to be thinking clearly or you have lost the ability to problem solve, NooCube is designed with you in mind. Instead of just masking these symptoms, NooCube assumes that you have toxins that are negatively affecting the brain, or you may be deficient in certain nutrients that are necessary for optimal cognitive function. Whatever the cause, this nootropic supplement can help you feel more like yourself again.

The Nootropic Formula

There are 13 specific ingredients included in NooCube. This includes bacopa, the herbal ingredient Huperzia serrata, pterostilbene, resveratrol, L-theanine, L-tyrosine, Alpha GPC, oat straw extract, cat’s claw, vitamin B1, vitamin B7 and vitamin B12. Also included in NooCube is Lutemax 2020, which is a marigold flower-derived supplement that contains three critical eye-brain nutrients (lutein and two unique zeaxanthin isomers).

What I Like

noocube three bottles

NooCube is another caffeine-free nootropic option. It provides you with better mental clarity by simply using natural and safe ingredients. You can go from scattered and stressful thinking to being clear headed and focused like you’ve never experienced before.

What I Don’t Like

This is a slightly expensive nootropic option. You can save a bit of money by purchasing multiple bottles of product at one time, but this isn’t something I feel comfortable doing until I’ve tried a product for a substantial amount of time. You are covered by a 100 percent, money-back guarantee for 60-days after the date of purchase.

Cost and Where to Buy

The current cost of NooCube is $59.99 for one bottle of product. If you buy three bottles of product at once, the cost is a discounted $119.99. You also gain access to a newsletter from the brand that provides additional information regarding how you can life a healthy lifestyle that will support your brain function. More information can be found at https://noocube.com/.

Comparing Nootropic Formulas

Even as a self-proclaimed wellness expert, I can easily become overwhelmed when trying to compare different supplement brands. There’s so much to take into consideration, especially when you’re considering the purchase of a nootropic. These three brands that I’ve talked about in this article (Thesis, Alpha Brain and NooCube) all bring something different to the table.

I prefer Thesis over the other options because of their personalized approach. You don’t have to worry about taking ingredients that you don’t need, and there won’t be anything missing from your formulation. You can’t get more exact than that. I also like Alpha Brain. Their proprietary blends are very precise, including high-quality and effective ingredients.

Comparing Effectiveness of Nootropics

In regard to Thesis, I personally can tell you that I’ve used their product. I’ve found it to be very effective. Thesis is a very established brand, but they don’t include a lot of ratings or reviews on their website. I find that disappointing, but really, your experience matters most.

Alpha Brain has been used by millions of people with impressive results. It has a 3.8 star rating out of five stars on the company’s website, with over 4,500 reviews listed. People have used this product to boost performance at work, to help stay on task and to feel more energized. There doesn’t seem to be any unpleasant side effects to worry about.

NooCube has a section of their website dedicated to reviews, but this is another instance where there’s not a great deal of ratings included. You can find some personal stories and reviews elsewhere on the internet if you’d like to learn more about what people have experienced.

Comparing Pricing

As I mentioned, the price of Thesis Nootropics is $119 for a one-time purchase, and $79 if you choose the Thesis monthly subscription service. This is a bit higher of a price tag than the other nootropics in this article, but you have to expect the cost to be a little higher when you’re getting a personalized supplement.

The cost of Alpha Brain is currently $63.96, so it’s a little lower than Thesis’ option. NooCube is your most affordable option, priced at $59.99 for one bottle.

Main Differences between Alpha Brain, NooCube Vs. Thesis Nootropics

Collage of three nootropics

Thesis Nootropics stands out because of the personalization aspect this company provides. There is an impressive selection of ingredients available for whatever blend is suggested for you. This is the one brand of the three that offers caffeine as an option.

Alpha Brain offers a number of ingredient options as well, but they are included by way of proprietary blends. You don’t get to choose what you want. NooCube includes separate ingredients in its formulation (except for the added Lutemax), but I feel like it’s a bit limited of a formulation.

Which Nootropic is Better: Thesis, Alpha Brain or NooCube?

I’m definitely going to choose Thesis for their personalization factor, as well as their use of quality and potent nootropic ingredients. If you’re hesitant to try something that has been made for you, Alpha Brain is the next best thing. It’s a really versatile blend that will help with cognitive functions like concentration, focus, memory, attention and reaction time. NooCube is also a great option for those that want all the nootropic benefits as well as protecting your eyes from “screen fatigue.”

The Bottom Line

My personal experience with ADHD, Adderall and nootropics has led me down the path to becoming a wellness enthusiast. I have come to understand just how effective and beneficial natural ingredients can be. Thesis, Alpha Brain and NooCube all provide very safe nootropic options that can help you with your cognitive health and brain function. Whether you are considering stopping the use of a prescription medication like Adderall (with the help of your doctor, of course), or this is your first attempt to tackle your brain fog, trouble concentrating and lack of focus, I’m confident you will find these three products top options for use in your own life.

Photo of author

Courtney D'Angelo, MS, RD

Courtney D'Angelo, MS, RD, earned her masters degree in Nutrition and Foods from the University of Georgia. She's a Registered Dietitian at Morrison Healthcare and has a strong passion in helping people improve their wellness!

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